Rachel H. Rose1, Kevin Feng1, David B. Turner1, Amin Rostami-Hodjegan1,2, Masoud Jamei1 1. Simcyp Limited (a Certara Company), Sheffield, UK; 2. Manchester School of Pharmacy, University of Manchester, UK • Following a meal, physiological changes occur that can impact upon drug absorption and elimination.

Erik Mosekilde; Olga Sosnovtseva; Amin Rostami-Hodjegan. Book. 11 Citations; 16k Downloads. Download book PDF · Download book EPUB. Chapters Table

Köp boken Biosimulation in Biomedical Research, Health Care and Drug Development hos oss! Jill Barber, Matthew R. Russell, Amin Rostami-Hodjegan, Brahim Achour. Characterization of CYP2B6 K262R allelic variants by quantitative allele-specific proteomics using a QconCAT standard. Journal of Pharmaceutical and Biomedical Analysis 2020, 178 , 112901.

Amin rostami-hodjegan

J Clin Psychopharmacol 2004; 24: 70 –8. Jiansong Yang, Masoud Jamei, Amir Heydari, Karen R. Yeo, Rafael de la Torre, Magí Farré, Geoffrey T. Tucker, and Amin Rostami-Hodjegan Journal of Psychopharmacology 2006 20 : 6 , 842-849 Download Citation Jiansong Yang, Masoud Jamei, Karen Rowland Yeo, Geoffrey T. Tucker and Amin Rostami-Hodjegan, “ Prediction of Intestinal First-Pass Drug Metabolism”, Current Drug Kairui Feng1, Robert H. Leary1, Michael Dunlavey1, Amin Rostami-Hodjegan1,2 1. Certara, USA; 2. University of Manchester, UK; email: kevin.feng@Certara.com USP 1 USP 2 USP 3 USP 4 Figure 1. In Vitro dissolution profiles (n=3) of nifedipine IR capsule in FaSSGF. FaSSGFst=FaSSGF at pH 1.6 with water, FaSSGFoj=FaSSGF at pH 3.4 with grapefruit juice Amin Rostami-Hochaghan (Participant) Impact : Cultural impacts, Economic impacts, Health impacts, Political impacts, Technological impacts Dosing for groups of patients who were not served previously by conventional drug information. Amin Rostami-Hodjegan.

There is increasing evidence to suggest that a strategy based on plasma drug monitor Hajar Al Feteisi, Brahim Achour, Amin Rostami-Hodjegan, Jill Barber, Translational value of liquid chromatography coupled with tandem mass spectrometry-based quantitative proteomics for in vitro – in vivo extrapolation of drug metabolism and transport and considerations in selecting appropriate techniques , Expert Opinion on Drug Metabolism & Toxicology, 10.1517/17425255.2015.1055245, 11, 9 Professor Amin Rostami‐Hodjegan, PharmD, PhD, FCP, Centre for Applied Pharmaceutical Research, Manchester Pharmacy School, University of Manchester, Stopford Building, Oxford Road, Manchester M13 9PT, UK. E‐mail: amin.rostami@manchester.ac.uk. Search for more papers by this author Abstract: In vivo enzyme levels are governed by the rates of de novo enzyme synthesis and degradation.

Jiansong Yang, Masoud Jamei, Karen Rowland Yeo, Geoffrey T. Tucker and Amin Rostami-Hodjegan, “ Prediction of Intestinal First-Pass Drug Metabolism”, Current Drug

Certara, USA; 2. University of Manchester, UK; email: kevin.feng@Certara.com USP 1 USP 2 USP 3 USP 4 Figure 1. In Vitro dissolution profiles (n=3) of nifedipine IR capsule in FaSSGF.

Model-informed precision dosing (MIPD) has become synonymous with modern approaches for individualizing drug therapy, in which the characteristics of each patient are considered as opposed to applying a one-size-fits-all alternative. This review provides a brief account of the current knowledge, pra …

Certara, USA; 2. University of Manchester, UK; email: kevin.feng@Certara.com USP 1 USP 2 USP 3 USP 4 Figure 1. In Vitro dissolution profiles (n=3) of nifedipine IR capsule in FaSSGF.

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Journal of Pharmaceutical and Biomedical Analysis 2020, 178 , 112901. AAPS J. 2016 Sep;18(5):1082-94.

This review provides a brief account of the current knowledge, pra … Amin Rostami-Hodjegan is Chief Scientific Officer at Certara USA, Inc. View Amin Rostami-Hodjegan’s professional profile on Relationship Science, the database of decision makers. In vivo enzyme levels are governed by the rates of de novo enzyme synthesis and degradation. A current lack of consensus on values of the in vivo turnover half-lives of human cytochrome P450 (CYP) enzymes places a significant limitation on the accurate prediction of changes in drug concentration-tim … 2012-12-13 Rachel H. Rose1, Kevin Feng1, David B. Turner1, Amin Rostami-Hodjegan1,2, Masoud Jamei1 1.
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Författare: Erik Mosekilde, Olga Sosnovtseva, Amin Rostami-Hodjegan; Format: Pocket/Paperback; ISBN: 9783709117644; Språk: Engelska; Antal sidor: 396

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Amin Rostami-Hodjegan's 405 research works with 11,975 citations and 7,405 reads, including: Six years of progress in the oral biopharmaceutics area - A summary from the IMI OrBiTo project

Amin Rostami-Hodjegan. Professor of Systems Pharmacology, University of Manchester, UK. Verified email at manchester.ac.uk - Homepage. Translational Modelling in Drug Development. Articles Cited by Public access. Title. Sort.

Amin Rostami-Hodjegan The gut wall consists of many biological elements, including enterocytes. Rapid turnover, a prominent feature of the enterocytes, has generally been ignored in the development

Manchester School of Pharmacy, University of Manchester, UK • Following a meal, physiological changes occur that can impact upon drug absorption and elimination. Jiansong Yang, Masoud Jamei, Karen Rowland Yeo, Geoffrey T. Tucker and Amin Rostami-Hodjegan, “ Prediction of Intestinal First-Pass Drug Metabolism”, Current Drug AAPS J. 2016 Sep;18(5):1082-94. doi: 10.1208/s12248-016-9959-1. Review. PubMed PMID: 27506526. 11: Chen R, Rostami-Hodjegan A, Wang H, Berk D, Shi J, Hu P. Application of a physiologically based pharmacokinetic model for the evaluation of single-point plasma phenotyping method of CYP2D6.

A current lack of consensus on values of the in vivo turnover half-lives of human cytochrome P450 (CYP) enzymes places a significant limitation on the accurate prediction of changes in drug concentration-time profiles associated with interactions involving enzyme induction and mechanism (time Editorial Board Bazigha Abdul-Rasool, Dubai Pharmacy College, Dubai, U.A.E Khosrow Adeli, The Hospital for Sick Children, Canada Shahin Akhondzadeh, Tehran University of Medical Sciences, Iran Massoud Amanlou, Tehran University of Medical Sciences, Iran Gholameza Amin, Tehran University of Medical Sciences, Iran Fatemeh Atyabi, Tehran University of Medical Sciences, Iran Mahdi Balali-Mood 演者： Amin Rostami-Hodjegan （Centre for Applied Pharmacokinetic Research, University of Manchester, UK ／Certara, Princeton, New Jersey, USA.）シンポジウム5（代謝・毒性 DIS 2） 2019年12月11日（水）9：30〜11：45 C会場（2F 中会議室201） Amin Rostami-Hodjegan, PhD, FCP Ping Zhao, PhD Workshop Programme 2021. Download: DDI-Workshop – 2021 – 1 st Announcement (PDF) Sunday, May 30 th, 2021 Editorial supervision of Pharmacological Reviews is shared jointly with the British Pharmacological Society and the Scandinavian pharmacological societies.. BOARD OF PUBLICATIONS TRUSTEES [1] Brahim Achour, Matthew R. Russel, Jill Barber, and Amin Rostami-Hodjegan, Simultaneous Quantification of the Abundance of Several Cytochrome P450 and Uridine 59-Diphospho-Glucuronosyltransferase Enzymes in Human Liver Microsomes Using Multiplexed Targeted Proteomics, Drug Metab Dispos 42:500–510 (2014) Author.